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53-16-7 Testosterone Anabolic Steroid Estrone Powder Form To Cause Of Breast Tenderness Or Pain

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53-16-7 Testosterone Anabolic Steroid Estrone Powder Form To Cause Of Breast Tenderness Or Pain

Brand Name : YC
Model Number : 53-16-7
Certification : ISO9001
Place of Origin : WUHAN CHINA
MOQ : 10g
Price : Negotiation
Payment Terms : T/T, Western Union, MoneyGram
Supply Ability : 10000 kg per month
Delivery Time : 4-7 working days
Packaging Details : According to your requirements
CAS : 53-16-7
Appearance : white powder
MF : C18H22O2
MW : 270.3661
Purity : 99%
Package : According to your requirements
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Estrone


cas:53-16-7
MF:C18H22O2
Purity:99%
MW:270.3661


Description:

Estrone (E1, and also oestrone) is an estrogenic hormone secreted by the ovary as well as adipose tissue with the chemical name of 3-hydroxyestra-1,3,5(10)-triene-17-one and the chemical formula C18H22O2. Estrone is an odorless, solid crystalline powder, white in color with a melting point of 254.5 °C and a specific gravity of 1.23. Estrone is one of several natural estrogens, which also include estriol and estradiol. Estrone is the least abundant of the three hormones; estradiol is present almost always in the reproductive female body, and estriol is abundant primarily during pregnancy.

Estrone is known to be a carcinogen for human females as well as a cause of breast tenderness or pain, nausea, headache, hypertension, and leg cramps in the context of non-endogenous exposure. In men, estrone has been known to cause anorexia, nausea, vomiting, and erectile dysfunction Estrone is relevant to health and disease states because of its conversion to estrone sulfate, a long-lived derivative. Estrone sulfate acts as a reservoir that can be converted as needed to the more active estradiol. It is the predominant estrogen in postmenopausal women.
Estrone was discovered and isolated by German chemist Adolf Butenandt.


Applications:

The official chemical name of estrone is 3-hydroxyestra-1,3,5(10)-triene-17-one with the chemical formula C18H22O2.
Estrone is also named aquacrine, bestrone, crinovaryl, folliculin, 1,3,5-estratriene-3-ol-17-one, estro-a, estronol, erystogen, 3-hydroxyestra-1,3,5(10)-trien-17-one, kestrone 5, propagon-s, menagen, theelin, theogen, destrone, aquacrine, crystogen, oestrin, 1,3,5(10)-estratrien-3-ol-17-one, 1,3,5(10)-oestratrien-3-ol-17-one, and oestrone.
Biosynthesis

Estrone is synthesized via aromatase from androstenedione, a derivative of progesterone. The conversion consists of the de-methylation of C-19 and the aromaticity of the 'A' ring. This reaction is similar to the conversion of testosterone to estradiol.

Estrone is a white, solid crystalline powder that is odorless. It has a melting point of 254.5 °C (490 °F) and has a specific gravity of 1.23. At high temperatures estrone is combustible and the products of combusting estrone are carbon monoxide (CO) and carbon dioxide (CO2).



Test Items
SpecificationTest Results
DescriptionWhite or almost white crystalline powderWhite crystalline powder
Melting Point191.0~193.0ºC192ºC
Loss of drying≤1.0%0.5%
Heavy Metal≤20ppm15ppm
TLCOnly one spotOnly one spot
Assay≥99.5%99.91%

Conclusion


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It complies with the USP 32.


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